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Symbol
Name
ID
Il15
interleukin 15
MGI:103014
Phenotype annotations related to hematopoietic system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
hematopoietic system phenotype
absent uterine NK cells
abnormal thymus cell ratio
enlarged spleen
abnormal CD8-positive, alpha-beta T cell differentiation
increased bone marrow cell number
decreased dendritic cell number
decreased NK cell number
increased NK cell number
abnormal T cell subpopulation ratio
decreased CD8-positive, alpha-beta T cell number
abnormal NK T cell number
decreased NK T cell number
decreased CD8-positive, gamma-delta intraepithelial T cell number
decreased memory T cell number
increased memory T cell number
decreased regulatory T cell number
increased lymphocyte cell number
abnormal lymphocyte morphology
abnormal T cell morphology
increased spleen white pulp amount
abnormal lymphocyte physiology
decreased IgG level
decreased IgM level
decreased immunoglobulin level
impaired natural killer cell mediated cytotoxicity
abnormal CD8-positive, alpha-beta T cell physiology
Availability Mouse Genotype
Il15m1Hwata/Il15m1Hwata
Il15tm1Imx/Il15tm1Imx
Tg(ACTA1-Il15)10941Lsq/0 *
Tg(ACTA1-Il15*)11650Lsq/0 *
Tg(H2-D-Il15)3304Clgr/?

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory